There has been a recent explosion in the number of identified disorders linked to protein misfolding in the endoplasmic reticulum (ER), resulting in ER entrapment of exportable proteins accompanied by the deterioration of cell and tissue function. We are exploring potential therapies including treatments designed to avoid ER protein folding overload, enhance endogenous ER chaperone activities, and promote ER-associated degradation of misfolded mutant proteins. It is intended that such therapies will limit cell stress and cell death, and promote restoration of normal cell and tissue physiology.
(all meetings are from 1:00 pm until 2:00 pm in 3515 BSRB)
March 8, 2017 – Amy Chang’s Lab
April 12, 2017 – Malini Raghavan’s Lab
May 10, 2017 – Billy Tsai’s Lab
June 14, 2017 – Ming Liu’s Lab
July 12, 2017 – Peter Arvan’s Lab